NextGenPCR™ | From hours to minutes | High throughput | Any assay

Ultra Fast qPCR Technology

cyQlone™ – Quantitative PCR at lightning speed!

Enhance your NextGenPCR™ workflow with the launch of cyQlone™, our blazing fast qPCR, a quantitative version of the NextGenPCR™ Thermal Cycler that allows analysis of PCR fragments in real-time.

cyQlone - qPCR - Quantitative thermal cycling at lightning speed

The newest system cyQlone™ is equipped with an on-board fiber optics module that can analyze fluorescence in 6 color channels (FAM, ROX, Cy5, ATTO425, TET, and Cy7). The innovative fiber optics system allows for extremely rapid fluorescence measurements, averaging a detection time of 20 milliseconds per channel per cycle.

Harboring the speed of NextGenPCR™ thermal cycling, our qPCR system cyQlone™ can amplify and analyze 96 multiplex samples in 9 minutes or less, making it the fastest SBS-format qPCR system on the planet.

Generating rapid PCR results is not the only thing our qPCR system cyQlone™ excels at. It boasts excellent sensitivity and robustness and has an ergonomical design. With a width of just under 20 cm, the system takes up very little space in the laboratory. The instrument is expected to work with all existing probe-based and intercalating dye RT-PCR chemistries. Proprietary high-speed NextGenPCR™ qPCR chemistries are also available from MBS. NextGenPCR™ chemistry allows users to enjoy the full speed of their qPCR system.

cyQlone™ isn’t just faster qPCR. It’s a whole new cycle.

From pathogen detection to microbial surveillance and plant genotyping, it delivers actionable results in minutes — helping your lab respond faster, screen smarter, and conserve valuable resources.

Advantages of our qPCR system cyQlone™

  • Versatile qPCR setup: 6 channel detection capability (FAM, ROX, Cy5™, ATTO425, TET, Cy7™)
  • Generate accurate results: ultrafast and precise temperature control
  • Environment friendly: saves energy and produces less plastics waste
  • Save benchtop space: space efficient instrument suitable for any laboratory setup

Technical Specifications

Name cyQlone™
Application Quantitative PCR
Process time ≥ 9 minutes (incl. 6 channel detection)
Detection Built-in fibre optics
Detectiemethode 6 channel fluorescence (FAM, ROX, Cy5™, ATTO425, TET, Cy7™)
Sample format 96-well SBS microplate format
Sample volume 5-20 uL
Footprint 20 cm width

Applications

Applications for quantitative PCR cover a wide range of life science fields. The qPCR instrument cyQlone™ can help in accelerating turnaround times for countless quantitative real-time PCR applications.

Pathogen detection

In clinical research rapid outcomes of molecular tests are crucial for adequate patient care. Quantitative PCR is used to for example detect pathogenic species in clinical samples or investigate gene expression of human tissues to detect disease states. Obtaining a fast diagnosis leads to better clinical decision making for available treatments, less waiting times and improved patient outcomes.

Microbial surveillance

With the ever increasing threat of emerging pandemics, genome surveillance of microbial strains is becoming a focal point of microbiologists around the globe. Rapid microbial characterization methods are vital for mediating outbreak threats, generating insights into circulating microbial strains and guide public health decisions.

Plant & animal genotyping

Genetics studies for plant and animal breeding purposes have historically been employed to increase yields and improve resistance to diseases and changing environmental conditions. Breeding applications are characterized by large sample numbers that require high-throughput setups, and are dependent on generating data quickly in order to streamline continued breeding potential.

 


Example qPCR detection methods available:

  • Gastrointestinal pathogens (viruses, bacteria, parasites)
  • C. difficile
  • E. coli
  • SARS-CoV-2
  • Influenza A/B
  • Parainfluenza
  • RSV
  • Mpox virus
  • SNP characterization with PACE™ assays

Other application fields, such as environmental monitoring (biodiversity, soil quality) and food safety (spoilage, drink water safety) are also benefited by the rapid qPCR capabilities of the qPCR system. Please contact us if your application is not mentioned above to find out about custom PCR designs and tailored technical support.

Let’s get started as soon as possible:

To inquire about our blazing fast qPCR system cyQlone™, please contact us via the contact form below.

Quantitative thermal cycling at lightning speed